Project Information

Therapeutic enoxaparin in neurocritical care patients

Project Description: Enoxaparin package insert directs to use actual body weight when calculating therapeutic enoxaparin doses. Enoxaparin has a small volume of distribution and dosing on actual body weight likely leads to supratherapeutic levels in obese patients. This review aims to evaluate enoxaparin dosing and levels from patients in the NeuroICU for guidance on patient parameters that may prompt weight-based dose adjustments.

QPI: Aimee, Gowler, (



UF Health Big Aims: Zero Harm None

MeSH Keywords: Obesity, Pharmacokinetics, Enoxaparin, Anticoagulation