Project Information

Detection of Herpes Simplex Virus via PCR in Cerebrospinal Fluid Samples: Rates of Detection and Impact on Length of Stay and Management

Project Description: The detection of herpes simplex virus via PCR (polymerase chain reaction) is an important diagnostic tool for patients with meningitis and/or encephalitis. We plan to analyze data from our institution's LIS (Epic/Beaker) as it pertains to pediatric and adult cerebrospinal fluid specimens that have been tested for HSV via PCR. The results of this project can demonstrate how the HSV PCR can reduce patient harm by decreasing the length of stay and preventing administration of unnecessary antiviral therapy.

QPI: Maira, Gaffar, (

Collaborators: Jennifer, Reppucci, (; Maira, Gaffar, (

Advisors: (

UF Health Big Aims: Zero Harm None

MeSH Keywords: Acyclovir, Encephalitis, Herpes Simplex, Length of Stay, Meningitis, Polymerase Chain Reaction