Project Information

Evaluation of Latent TB Infection Screening in Outpatient Primary Care Clinics and Development of Possible Interventions

Project Description: The U.S. Preventive Services Task Force's most recent recommendations for TB has included latent TB infection (LTBI) screening for populations at increased risk for TB disease, both in the private and public setting. Traditionally, public health clinics—namely health departments—have handled LTBI screening. However, for TB elimination in the United States, there must be a massive scale-up of LTBI testing and treatment in populations at risk for TB disease; more than 80% of TB disease cases are due to reactivation of latent TB infection. For this reason, the U.S. Preventive Services Task Force (USPSTF) has most recently recommended that primary care clinics perform LTBI screening and treatment in populations at increased risk for TB disease. Our project, which stems from the CDC-funded TB Epidemiologic Studies Consortium, aims to assess the current practices related to LTBI testing and treatment at UF outpatient primary care clinics, and the extent to which these practices comply with the USPSTF’s recommendations. We are interested in measuring extent to which a key population—foreign-born persons from countries with medium to high TB incidence rates—participates in LTBI services (screening, testing, medical evaluation, recommendation for treatment, and treatment completion). Based on this data, we will then invite the clinics to participate in discussions about barriers and facilitators to scaling up LTBI screening and treatment. Lastly, we will work with the key personnel at each clinic to identify feasible interventions that address these barriers and enhance the facilitators.

QPI: Joanne, Li, (

Collaborators: (

Advisors: (; Marie, Seraphin, (

UF Health Big Aims: Reduce Variation None

MeSH Keywords: Latent TB Infection, Latent TB Epidemiology, Latent TB Diagnosis, Emigrants and Immigrants, Latent TB Prevention and Control