Project Information

Utilizing intranasal mupirocin to reduce incidence of cardiac surgery surgical site infections

Project Description: Sternal wound infections are associated with increased morbidity, mortality and decreased long term life expectancy. Infections can raise hospital cost by $62,000 per admission. Despite clinical and economic consequences there are no specific guidelines for prevention or treatment of sternal would infections, however prevention recommendations do exist. Preoperative intranasal mupirocin administration was chosen as for high risk group as part of UF Health's decolonization protocol. As such, the cardiac surgery physicians and/or extenders will prescribe and educate patient on mupirocin use as part of clinic pre-op visit. Mupirocin use will be documented in nursing flowsheet at admission. Compliance reporting will be shared with service on monthly basis.

QPI: Cristina, Crippen, (

Collaborators: Juan, Gallegos, (; Kae, Pearson, (; Thomas, Beaver, (


UF Health Big Aims: Zero Harm None

MeSH Keywords: SSI, surgical site infection, infection, decolonization, hosptial acquired infection